Professor Ambrose O. Isah graduated from the University of Ibadan Medical School in 1979 and had his postgraduate training in Internal Medicine at the University of Benin Teaching Hospital, Nigeria. He had his postgraduate training in Clinical Pharmacology and Therapeutics at the Wolfson Unit of Clinical Pharmacology, University of Newcastle Upon Tyne, United Kingdom obtaining his doctorate degree (MD) in 1995. He is a Fellow of the National Postgraduate Medical College of Nigeria, the West African College of Physicians and the Royal College of Physicians, Edinburgh.

He is a Consultant Physician and Clinical Pharmacologist at the University of Benin Teaching Hospital, Benin City. Professor Isah has served on the academic staff of the University of Benin Medical School since 1989. He is a Past Dean of the Medical School; Past Head Department of Internal Medicine and pioneer Head of the Department of Clinical Pharmacology and Therapeutics. Professor Isah is the Pioneer Chairman of the Internal Medicine Subspecialty of Clinical Pharmacology and Therapeutics of the West African Postgraduate Medical College and Past Chairman of the Subspecialty of the National (Nigerian) College. He is the immediate Past Chairman of the National Essential Medicines/Drug Formulary Committee

Professor Isah played a key role in the establishment of the Pharmacovigilance system in Nigeria.  He is the current Chairman of the National Drug Safety Advisory Committee (NAFDAC; MOH) and Immediate Past Vice President of the African Society of Pharmacovigilance (ASoP).

Prof Isah was the Lead in the development of the WHO reference standards for the Drug Use Indicators as well as the WHO Pharmacovigilance Indicators.  He served as a member of the WHO Expert Panel and Advisor to the WHO Uppsala Monitoring Centre, Uppsala, Sweden. He was a Work Package Lead of PAVIA an EDCTP sponsored Pharmacovigilance Project in Africa

Prof. Isah is a recipient of the University of Ibadan Most Distinguished Alumnus Award 2021; a Fellow of the Nigerian Academy of Medicine; a Fellow of the British Pharmacological Society and a Fellow of the West African Society of Pharmacology. A keen lover of sports, documentary movies, he is married with three children.